Explore the Southeastern Missouri Area
of the Meeting the Ohio River Region

greatriverroad.com coverage of Southeast Missouri consists of four counties: Perry, Cape Girardeau, Scott, and Mississippi. Communities covered in this region include Cape Girardeau, Sikeston, Jackson, and Charleston. The area offers visitor opportunities to explore the historical, cultural and natural aspects of the region.

Saxon Lutheran Memorial Frohna, Missouri

Saxon Lutheran Memorial
Frohna, Missouri

Perry County, Missouri

Perry County is a county that typifies rural Missouri. The history of early Missouri can be explored at such locations as the Lutheran Heritage Center, St. Mary's of the Barrens, and the Saxon Lutheran Memorial. Tower Rock Conservation Area provides a viewing platform that offers a scenic view of Tower Rock, a small landmark limestone noted by early explorers such as Marquette and Joliet and the Corps of Discovery. A day trip through Perry County in autumn will reward visitors with plenty of splashes of color amidst the rolling farmland.

Trail of Tears State Park Jackson, Missouri

Trail of Tears State Park
Jackson, Missouri

Cape Girardeau County, Missouri

Visitors to Cape Girardeau County will find an abundance of attractions of all varieties. The city of Cape Girardeau itself boasts a number of historical and cultural museums including the Crisp Museum, Cape River Heritage Museum, the Glenn House, and Lorimier's Trading Post. Bollinger Mill State Historic Site near Jackson is unusual in that it features both a workable mill and a covered bridge, side by side. The Cape Girardeau Conservation Nature Center showcases the rich cultural history and diverse natural resources of Southeast Missouri. Trail of Tears State Park offers camping, fishing, swimming, hiking, backpacking, primitive camping and equestrian pursuits.

Sikeston Deport Museum Sikeston, Missouri

Sikeston Deport Museum
Sikeston, Missouri

Scott County, Missouri

Culture history and nature can all be found in Scott County. The Sikeston Depot was revitalized and became the Sikeston Historical and Cultural Center containing a historic museum and an art gallery. Sikeston offers a driving tour of more than 24 magnificent homes constructed during the early 1900s. Just outside of Sikeston is the Southeast Missouri Agriculture Museum, which boasts the state´s largest collection of antique farm machinery. The General Watkins Conservation Area contains a forest type more closely resembling Appalachian than Missouri forests.

Big Oak Tree State Park East Prairie, Missouri

Big Oak Tree State Park
East Prairie, Missouri

Mississippi County, Missouri

Missouri starts to take on a Deep South flavor in Mississippi County. The Moore House and a museum dedicated to former Governor Warren E. Hearnes can be found in the town of Charleston. The past can be explored by seeing what the region looked like before being drained for farmland at Big Oak Tree State Park or by visiting the site of a prehistoric Native American village at Towosahgy State Historic Site. Visitors can ride the river by crossing the Mississippi River to Kentucky on the Dorena-Hickman Ferry.

Explore the Meeting the Ohio River Region